Ligand binding Study guides, Class notes & Summaries

Cell Signaling and Apoptosis Types of Signaling • A ligand is a molecule that has specificity for a given receptor, and the binding of a ligand to the given receptor causes a change. • There is a wide array of cell ligands: hormones, peptides, sugars, and even small, hydrophobic molecules. • Regardless of its type, a ligand is always specific for the target receptor. This ligand-to-receptor specificity helps to regulate responses in the target cell while not impacting non-target cell...

BIOC3560 F17 Midterm Exam Questions With Answers Latest 2023/2024. Select the statement that accurately describes an O2-binding curve of a globin. (A) The heme-O2 binding curve is a sigmoidal curve. (B) Hemoglobin and myoglobin have reciprocal pO2-binding curves. (C) Hemoglobin has a sigmoidal O2-binding curve. *** (D) Myoglobin has a sigmoidal O2-binding curve. (E) All of the above. 2. Which statement is false with respect to enzyme phosphorylation? (A) The modification is irreversible. ...

VCU Biochem Exam 2 Questions And Answers is binding of ligands reversible? - ANS-yes, it is essential for it to be reversible cooperativity - ANS-In multisubunit proteins, conformational changes in one subunit can affect the others functions of globular proteins - ANS-1. storage of ions and molecules (myoglobin and ferritin) 2. transport of ions and molecules (hemoglobin, serotonin transporter) 3. defense against pathogens (antibodies, cytokines) 4. muscle contraction (actin, myosin) 5....

PCOL 824 UA Exam Questions with Correct Answers Different drug receptors (4) - Answer-Ligand-gated ion channels G-protein coupled receptors Catalytic receptors Intracellular receptors Ligand-gated ion channels - Answer-Extracellular ligand-binding site Transmembrane receptor Typically closed will open when active Type of ion conducted through channel determines response eg. Nicotinic ACh receptor G-protein coupled receptors - Answer-When binding occurs on the extracellular side, ...

Chemical signal correct answers Cell signal that allows experience of odor and taste; includes hormonal signaling Physical signal correct answers Cell signal that allows experience of sound, touch, and sight; must be converted into a chemical signal at the level of the receptor General principles of cell communication correct answers Includes the reception of an extracellular signal molecule, the transduction of the signal through intracellular signaling proteins, and then the use of secon...

Membranes (both outside and inside the cell) correct answer: Not a static structure, very important for cell function. They contain proteins that are very complex and vital to cell life. Mitochondria membranes correct answer: Very vital for the cell, has both an inner and outer membrane. What drives membrane formation? correct answer: A decrease in ionic interactions with water / limiting the hydrophobic interactions drives membrane formation. Lipid tails are ... correct answer: Hyd...

PCB exam 1 questions & answers 2023/2024 Globular proteins fold up into compact, spherical structures that have uneven surfaces. They tend to form multisubunit complexes, which also have a rounded shape. Fibrous proteins, in contrast, span relatively large distances within the cell and in the extracellular space. Which of the proteins below is not classified as a fibrous protein? - ANSWER-Elastase (the ones that are: keratin, collagen, and elastin) Which of the following statements is tr...

GMS 6504 MODULE 1-3 EXAM 1 REVIEW QUESTIONS AND ANSWERS, RATED A+ What are System Independent Parameters? - -Affinity Efficacy What are the parts of a system that are identified as System Dependent Parameters? - -Number of receptors Cellular machinery Presence of other drugs - Competitive - Noncompetitive Affinity is - -Thermokinetic propensity of drug to bind to receptor Based largely on ΔG Efficacy is - -Magnitude of change of receptor shape/function upon drug binding Base...

PHR 4000 Exam 1b Questions & Answers 2023/2024 MOA - ANSWER-mechanism of action What must be considered for pharmacodynamics of a drug? - ANSWER--Binding of the drug to its target -How the drug affects the target function -The resulting physiological response What are the limitations of drugs? - ANSWER-•They can only modify existing* functions of cells -Mimic or inhibit the action of an endogenous ligand - they interact with other biomolecules resulting in a physiological effect...

Bio 219-exam 2 review DHL questions & answers 2023/2024 Which of these can be detected for signaling? A. Heat B. light C. Molecules D. Any of these can be detected if the right receptor is present - ANSWER-D Which of these is true about ligand/receptor interactions? A. Each receptor can bind many kinds of ligands B. Each ligand can bind many kinds of receptors C. Ligand/receptor interactions are highly specific due to binding affinity D. The outcome of the ligand/receptor binding...